Alex is awake but still not back to her old self, and Dawn has given strict orders for her recovery plan. Meanwhile, Charlie and Joel square-off over differing treatment options when two fused-together burn victims are brought into the ER. Maggie finds herself in a whirlwind of emotions triggered from the fallout of her miscarriage.

When Hope Zion Hospital's Chief of Surgery, Charlie Harris ends up in a coma, he finds himself wandering the halls in spirit form. Stuck between worlds, he watches as his fiancée and the staff of the hospital fight to keep patients - and hope - alive.