Kogoro, Ran, and Conan are staying at a hotel when they run into Kogoro's estranged wife, Eri Kirisaki. Eri is at the hotel with colleagues of hers. Kogoro is upset seeing Eri around another man and proceeds to get drunk. He is later found in the bed of Eri's female colleage, who has been murdered!

Kudo Shinichi is a seventeen year-old high school detective whom people call the "Modern Sherlock Holmes." However, one night after a date with his childhood sweetheart, Ran, Shinichi witnessed an illegal trade and, caught off his guard, was knocked unconscious and fed a drug that was supposed to kill him... but he woke up and found himself shrunken to a seven year-old. In order to track down the men who did this to him, Shinichi hid his identity and lived with Ran, whose father happened to be a hopeless detective, and with that came a series of murders and mysteries that he must solve.