After being stabbed in the heart, Alex has a profound experience in the liminal space, while a desperate Charlie and Dawn race against the clock to save her life. Meanwhile, Joel is pulled in to the ER to treat a suicidal patient that tests his duty as a doctor, and Maggie makes a bold decision that changes her relationship with Gavin.

When Hope Zion Hospital's Chief of Surgery, Charlie Harris ends up in a coma, he finds himself wandering the halls in spirit form. Stuck between worlds, he watches as his fiancée and the staff of the hospital fight to keep patients - and hope - alive.